Carsten Prasse, Assistant Professor
My research is driven by a fascination with environmental chemistry and a deep concern about the public and environmental health impacts of chemicals present in our environment. My research group investigates the fate of contaminants in the built and natural environment using state-of-the-art analytical chemistry techniques (e.g. high-resolution mass spectrometry) with the focus on identifying transformation products and understanding underlying mechanisms of transformation. One of our main areas of interest is presence of contaminants in the urban water cycle. Even though the efficacy of treatment technologies is still primarily evaluated based on the removal of well-known trace organic contaminants, our research has clearly demonstrated the relevance of transformation products with some of them even being present in our drinking water.
The recognition of the relevance of transformation products as emerging class of water contaminants led to a series of studies in which we investigated the fate of transformation products in treatment trains used in both wastewater treatment and drinking water purification. This was paired with in vitro and in silico toxicological approaches to assess the toxicity of the transformation products. The results have clearly demonstrated that degradation processes can result in transformation products that exhibit an increased toxicity compared to the parent chemicals. This is particularly relevant for the assessment of new treatment technologies as well as alternative drinking water resources, in particular regarding water reuse.
One widely unanswered question is how to prioritize the compounds that are present and how to identify which compounds are most threatening to human and environmental health given that thousands of chemicals are present in our waters. To tackle this problem, our research focuses on using concepts and methods from toxicology and public health. This work is interdisciplinary with the goal of developing new methodologies to inform water treatment technology development, comprehensively assess water quality and characterize the Drinking Water Exposome.
Full list of publications: Google Scholar Citations
Veronica Wallace, PhD student
Environmental Health and Engineering forges interdisciplinary problem-solving approaches across many otherwise disparate disciplines. As a PhD student, I aim to undertake training and research at the confluence of public health, environmentalism, and engineering, targeting issues of immediate concern in our local community and global environment. My research interests are shaped by the environmental and health disparities I have witnessed living in the city of Baltimore, and also by my long-standing interests in medicine and individual health. After completing my BA in Anthropology at Yale University, I received my Master’s of Science in Bioengineering from the University of Pennsylvania. I made my foray into Public Health interning at the World Health Organization in Geneva, Switzerland, with the unique opportunity to bring experience in biomedical engineering to work in the Department of HIV/AIDS Key Populations and Innovation Prevention Team. My post-grad work has since spanned clinical and biomedical research. I moved to Baltimore, MD to work with Dr. Bruce Hope at the NIH National Institute on Drug Abuse, and continued to develop my interests in environmental and public health living and working in Baltimore. Prior to starting my PhD in summer 2018, I worked with a biotech startup in Baltimore. Returning to academia and embarking on my doctoral degree, innovation and interdisciplinary problem-solving are at the forefront of my research endeavors.
Chris Brueck, PhD student
I developed a strong passion for environmental engineering and science in college after working with a research team to help remediate the ecological devastation caused by the Valdez and Deepwater Horizon oil spills. Since then I have spent my efforts studying the fate of contaminants in natural and engineered environments using both experimental- and modeling-based approaches. After receiving my MS in Environmental Engineering (2016) from Oregon State University on the topic of colloid transport in the vadose zone, I returned to my hometown of Baltimore to start a PhD program at Johns Hopkins University.
My current research focuses on the impact of organic contaminants on wastewater treatment and bioenergy production in anaerobic digesters. As a co-advised student in both the Prasse and Bouwer labs (EHE), I hope to bridge environmental chemistry and microbiology using state-of-the-art analytical and molecular tools so that we may better relate chemical transformations, microbial inhibition, and overall reactor “process upsets.” To this end, we employ high-resolution mass spectrometry for metabolomics and non-targeted chemical analysis to realize connections between pharmaceuticals (human and veterinary) and microbial metabolism occurring in anaerobic digesters. With this information we will propose improvements to the wastewater treatment paradigm in municipal and agricultural settings and assess options for sludge and digestate recycling.
Outside of the lab you will find me playing local gigs as the guitarist in my band or eating too much food at one of the many awesome restaurants around Baltimore!
Zhuoyue Zhang, PhD student
As the generation born after 1995, I witnessed the rapid deterioration of river systems in my hometown, Xiangyang, which is a miniature scenario of ecosystem status in China under the big background of high-speed economic development. Since my first research project as an undergraduate student on utilization of Advanced Oxidation Processes with assistance of homemade catalysts to degrade dyes in aqueous system, I’ve been intentionally focusing my research interest on water resource and treatment issues. Since majoring in environmental engineering I have never been more compelled about my responsibility since majoring in environmental engineering majored student after the 12 weeks research internship program in University of Saskatchewan, Canada. It is not because of how interesting my first research experience abroad was, but simply of a camping trip to a small lake there. The purity, the transparency and the beauty of the lake water touched my heart so profoundly that it inspired me to continue my study and research on environmental issue. All of these journeys added up to lead me here to work in the Prasse lab. I really enjoy the interesting research topics and open atmosphere in the lab and strongly believe this research experience will be one of the most unforgettable memories in my whole life.
Melody Multra, Undergraduate student
Annabel Mungan, Undergraduate student
Previous lab member:
- Sara Nason (Postdoc): current position: research scientist at the Connecticut Agricultural Research Station
- Ximin Hu (Master’s student): current position: PhD student University of Washington, Department of Civil & Environmental Engineering
- Rafael Ferguson (undergraduate Student): current position: Master’s student Johns Hopkins University, Environmental Health & Engineering